Senior Director of Manufacturing Operations, Commercial

Are you a strategic manufacturing leader passionate about biologics and gene therapy?

Do you have the expertise to oversee GMP operations in a commercial manufacturing environment?

Ready to shape the future of life-enhancing therapies while driving operational excellence?

Fraser Dove International is partnering exclusively with a

leading life sciences organisation. Operating across a global footprint, they are committed to transforming patient lives through the development and delivery of life-changing treatments.

Our client is seeking a dynamic leader to oversee and optimise commercial manufacturing operations within a GMP environment.

Discover more about our Senior Director of Manufacturing Operations, Commercial opportunity; its objectives, duties/responsibilities and the skills, experience and competencies

needed to succeed.

Your objectives:

As the Senior Director of Manufacturing Operations, Commercial, you will be measured against the

following objectives:

Lead, manage, and develop commercial manufacturing teams to deliver products on time and in full
Ensure successful tech transfer and scale-up of commercial manufacturing campaigns
Drive operational efficiency through lean methodologies and continuous improvement initiatives

What you will do:

As the Senior Director of Manufacturing Operations, Commercial, your duties and responsibilities will include:

· Oversee multiple teams and shifts across upstream and downstream commercial production operations.

· Ensure GMP compliance, process reliability, and inspection readiness across manufacturing areas.

· Partner with Tech Transfer teams to enable smooth and timely transition of projects into commercial production.

· Serve as key point of contact for client interactions, providing updates, managing expectations, and ensuring satisfaction.

· Lead operational governance and performance systems including scheduling, risk management, and KPI delivery.

· Champion cross-functional collaboration with HR, MS&T, and senior leadership to attract talent and meet business goals.

· Support lean transformation efforts and drive waste reduction and efficiency improvement across operations.

What you will bring:

These are the skills and experience you will need to succeed as the Senior Director of Manufacturing Operations, Commercial:

· 10–12+ years’ experience in GMP biologic drug substance manufacturing.

· Experience leading upstream/downstream operations in mammalian or microbial systems.

· Strong CDMO/CMO and branded company experience.

· Proficiency in chromatography, TFF, CIP, and other purification techniques.

· Strategic leadership capabilities with at least 6 years of management experience.

· B.S. in Engineering or Life Sciences.

· M.S. in Engineering or Life Sciences (preferred).

Got what it takes?

To apply for the Senior Director of Manufacturing Operations, Commercial, click the ‘Apply’ button below or contact the Executive Search Consultant – [REECE WIGGINS] – on +44

(0)203 355 7050.

Please Note:

· This job description in no way states or implies

that these are the only duties to be performed by the employee(s) incumbent in

this position. Employee(s) will be required to follow any other job-related

instructions and to perform any other job-related duties requested by any

person authorised to give instructions or assignments.

· If you have not heard from an Executive Search

Consultant within ten working days from the date of your application, please

consider yourself unsuccessful on this occasion.

· We use the information in your application to

support your job search, contact you with relevant opportunities and to improve

our services.

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https://www.fraserdove.com/privacy-policy/

Fraser Dove International is a specialist executive search

firm operating exclusively in the life science industry. Passionate about

people, we take pride in helping exceptional life science organisations source

the talent they need to design, manufacture and distribute life-changing drugs,

treatments and devices which transform and save patient lives.

Let me know if you'd like this adapted to a slightly different tone or audience.

Fraser Dove International

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